Late-night eating and melatonin may impair insulin response

Duration: 4:50
Posted: April 2, 2019
By FoundMyFitness

Melatonin isn’t just a sleep hormone. In its role as a regulator of circadian rhythm, it regulates over 500 genes. One of the important functions emerging evidence suggests it plays is in the regulation of insulin production in the pancreas, where it binds to receptors and signals the temporary (overnight) suppression of insulin production.

This wasn’t a problem in our pre-industrial past, but in today’s environment of 24-hour food availability, it can have far-reaching effects on health. When food consumption regularly occurs outside normal daylight hours, the risk of hyperglycemia – higher than optimal blood glucose levels – increases. Chronic exposure to elevated glucose increases our risk of developing diabetes and other metabolic disorders. But, over time, elevated blood sugar – even within just high normal ranges – has an association with brain volume losses in the hippocampus and the amygdala, areas involved in memory and cognition.

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About FoundMyFitness: Rhonda Patrick has a Ph.D. in biomedical science from the University of Tennessee Health Science Center, and St. Jude Children’s Research Hospital. She also has a Bachelor’s of Science degree in biochemistry/chemistry from the University of California, San Diego. She has done extensive research on aging, cancer, and nutrition.

It is Dr. Patrick’s goal to challenge the status quo and encourage the wider public to think about health and longevity using a proactive, preventative approach.

Learn more about Dr. Rhonda Patrick and her mission for FoundMyFitness at

This video was originally published by FoundMyFitness


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